MCM3 Antibody - Cat. #: CSB-PA013591ESR1HU

SKU: CSB-PA013591ESR1HU

Size :50ul

Clone Number:

Aliases:Cervical cancer proto oncogene 5 antibody; DNA polymerase alpha holoenzyme associated P1 antibody; DNA polymerase alpha holoenzyme associated protein P1 antibody; DNA polymerase alpha holoenzyme-associated protein P1 antibody; DNA replication factor MCM3 antibody; DNA replication licensing factor mcm3 antibody; HCC 5 antibody; HCC5 antibody; hRlf beta subunit antibody; Human cervical cancer proto oncogene 5 antibody; MCM 3 antibody; mcm3 antibody; MCM3 minichromosome maintenance deficient 3 antibody; MCM3_HUMAN antibody; MGC1157 antibody; Minichromosome maintenance complex component 3 antibody; Minichromosome maintenance deficient 3 antibody; Minichromosome maintenance protein 3 antibody; P1 h antibody; P1 MCM3 antibody; P1 Protein antibody; P1-MCM3 antibody; P1.h antibody; p102 antibody; P102 protein antibody; Replication licensing factor beta subunit antibody; RLF beta subunit antibody; RLF subunit beta antibody; RLFB antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P25205

Immunogen:Recombinant Human DNA replication licensing factor MCM3 protein (1-295AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC, ChIP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \\\'once per cell cycle\\\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MCM3

Research Areas:Epigenetics and Nuclear Signaling