MCL1 Antibody - Cat. #: CSB-PA274877

SKU: CSB-PA274877

Size :100ul

Clone Number:

Aliases:Bcl 2 related protein EAT/mcl1 antibody; Bcl-2-like protein 3 antibody; Bcl-2-related protein EAT/mcl1 antibody; BCL2 related antibody; Bcl2-L-3 antibody; BCL2L3 antibody; EAT antibody; Induced myeloid leukemia cell differentiation protein Mcl 1 antibody; Induced myeloid leukemia cell differentiation protein Mcl-1 antibody; MCL 1 antibody; MCL1 antibody; MCL1-ES antibody; mcl1/EAT antibody; MCL1_HUMAN antibody; MCL1L antibody; MCL1S antibody; MGC104264 antibody; MGC1839 antibody; Myeloid Cell Leukemia 1 antibody; Myeloid cell leukemia ES antibody; Myeloid cell leukemia sequence 1 antibody; Myeloid cell leukemia sequence 1 BCL2 related antibody; Myeloid cell leukemia sequence 1 isoform 1 antibody; OTTHUMP00000032794 antibody; OTTHUMP00000032795 antibody; TM antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q07820

Immunogen:Peptide sequence around aa.148~152(N-N-T-S-T) derived from Human MCL1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Bingle C.D., Craig R.W., Swales B.M., Singleton V., Zhou P., Whyte M.K.B.J. Biol. Chem. 275:22136-22146(2000)
Zhang D., Li F., Weidner D., Mnjoyan Z.H., Fujise K.J. Biol. Chem. 277:37430-37438(2002)
Leu J.I.-J., Dumont P., Hafey M., Murphy M.E., George D.L.Nat. Cell Biol. 6:443-450(2004)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MCL1

Research Areas:Cancer;Cell biology;Metabolism