MBNL3 antibody , Cat. # FNab05041

SKU: FNab05041

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T(TNNT2) pre-mRNA exon inclusion but induces insulin receptor(IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology(DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

Immunogen:muscleblind-like 3(Drosophila)

Synonyms:CHCR, MBLX39, MBXL

Observed MW:38 kDa

Uniprot ID:Q9NUK0

Reactivity:Human, Mouse

Tested Application:ELISA, IHC, WB

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID:55796

Research Area:Developmental biology