MAX(Phospho Ser11) Rabbit Polyclonal Antibody

SKU: BT-AP03544

Size:100μL

Background:The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members| which include Mad| Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation| differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Research_area:Epigenetics and nuclear signaling

Target_protein:MAX

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MAX

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):17600

UniProt accession:Human: P61244; Mouse: P28574; Rat: P52164

Synonyms:MAX ;Phospho Ser11; Protein max; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X

GeneID:Human: 4149; Mouse: 0; Rat: 60661