MAPKAPK3/MK3 Monoclonal Antibody

SKU: AN200072P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:MAPKAPK3

Target Synonym:MDPT;MAPKAP;MAPKAP-K;MAPKAPK3;3PK;MAPKAP-K3;MAPKAP3;MAPKAPK-3;MDPT3;MK-3;anti MAPKAPK3;Chromosome 3p kinase;EC 2.7.11.1;MAP kinase-activated protein kinase 3;MAPK activated protein kinase 3;MAPK3;MAPK-activated protein kinase 3;MAPKAP kinase 3;MAPKAPK 3;MDPT326;Mitogen activated protein kinase activated protein kinase;Mitogen activated protein kinase activated protein kinase 3;mitogen-activated protein kinase-activated protein kinase 3

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:IHC-P

Isotype:IgG2a

Clonality:Monoclonal

Clone NO.:4B6

UNIProt ID:Q16644

Accession:

Background:This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E44, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.

Concentration:1 mg/mL

Immunogen:Recombinant Human MAPKAPK3/MK3 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:50-1:200;

Calculated MW:

ObservedMW: