MAP2K5 Monoclonal Antibody

SKU: BT-MCA4461

Size:100μL

Background:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Research_area:Cancer, Cardiovascular, Signal transduction

Target_protein:MAP2K5

applications:WB, IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5H11B10

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MAP2K5

Immunogen:Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):50kDa

UniProt accession:Q13163

Synonyms:MEK5, MAPKK5, PRKMK5, HsT17454

GeneID:5607