MAP2 Monoclonal Antibody

SKU: AN200047P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:METAP2

Target Synonym:Methionine aminopeptidase;p67eIF;MAP;METAP2;MAP2;MNPEP;p67eIF2;MAP 2;MetAP 2;Methionine aminopeptidase 2;p67;Peptidase M;MAP2

Research Areas:Signal Transduction;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:6H12

UNIProt ID:P50579

Accession:

Background:The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 1. Several transcript variants encoding different isoforms have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human MAP2 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:1000;

Calculated MW:52 kDa

ObservedMW:60 kDa