MANF Polyclonal Antibody

SKU: E-AB-12987

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MANF

Target Synonym:Arginine rich mutated in early stage tumors;Arginine rich protein;Arginine-rich protein;ARMET;ARMET protein;ARP;Manf;MANF;Mesencephalic astrocyte derived neurotrophic factor;Mesencephalic astrocyte-derived neurotrophic factor;MGC142148;MGC142150;Protein ARMET

Research Areas:Cancer;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P55145

Accession:

Background:The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

Concentration:0.1 mg/mL

Immunogen:Synthetic peptide of human MANF

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:100-1:300

Calculated MW:

ObservedMW: