MAD2L1 Antibody - Cat. #: CSB-PA209741

SKU: CSB-PA209741

Size :50ul

Clone Number:

Aliases:HsMAD2 antibody; MAD 2 antibody; MAD2 like 1 antibody; MAD2 mitotic arrest deficient like 1 antibody; MAD2-like protein 1 antibody; Mad2l1 antibody; MD2L1_HUMAN antibody; Mitotic arrest deficient 2-like protein 1 antibody; Mitotic spindle assembly checkpoint protein MAD2A antibody; REV7 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13257

Immunogen:Fusion protein of Human MAD2L1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

Background:MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MAD2L1

Research Areas:Cancer;Cell biology