M4K5 Polyclonal Antibody

SKU: BT-AP11030

Size:100μL

Background:This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Research_area:Signal transduction

Target_protein:MAP4K5

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Mitogen-activated protein kinase kinase kinase kinase 5

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9Y4K4; Mouse: Q8BPM2

Synonyms:Mitogen-activated protein kinase kinase kinase kinase 5 ;EC 2.7.11.1;Kinase homologous to SPS1/STE20;KHS;MAPK/ERK kinase kinase kinase 5;MEK kinase kinase 5;MEKKK 5

GeneID:Human: 11183