M3K14 Polyclonal Antibody

SKU: BT-AP11027

Size:100μL

Background:This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Research_area:Cell biology ; Signal transduction; Epigenetics and nuclear signaling

Target_protein:MAP3K14

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Mitogen-activated protein kinase kinase kinase 14

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q99558; Mouse: Q9WUL6

Synonyms:Mitogen-activated protein kinase kinase kinase 14 ;EC 2.7.11.25;NF-kappa-beta-inducing kinase;HsNIK;Serine/threonine-protein kinase NIK

GeneID:Human: 9020