LONP1 Antibody, Biotin conjugated - Cat. #: CSB-PA013032LD01HU

SKU: CSB-PA013032LD01HU

Size :50ug

Clone Number:

Aliases:hLON antibody; hLON ATP dependent protease antibody; LON antibody; lon peptidase 1, mitochondrial antibody; LON protease antibody; Lon protease homolog antibody; Lon protease like protein antibody; Lon protease-like protein antibody; LONHs antibody; LONM_HUMAN antibody; LONP antibody; Lonp1 antibody; MGC1498 antibody; mitochondrial antibody; Mitochondrial ATP dependent protease Lon antibody; Mitochondrial ATP-dependent protease Lon antibody; Mitochondrial lon peptidase 1 antibody; PIM1 antibody; Protease serine 15 antibody; PRSS15 antibody; Serine protease 15 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P36776

Immunogen:Recombinant Human Lon protease homolog, mitochondrial protein (614-959AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LONP1

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism