LILRB4 Antibody - Cat. #: CSB-PA297929

SKU: CSB-PA297929

Size :100ul

Clone Number:

Aliases:CD85 antigen-like family member K antibody; CD85k antibody; HM18 antibody; ILT-3 antibody; ILT3 antibody; Immunoglobulin-like transcript 3 antibody; Leukocyte immunoglobulin like receptor subfamily B (with TM and ITIM domains) member 4 antibody; Leukocyte immunoglobulin-like receptor 5 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 4 antibody; LILRB4 antibody; LILRB5 antibody; LIR-5 antibody; LIR5 antibody; LIRB4_HUMAN antibody; Monocyte inhibitory receptor HM18 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8NHJ6

Immunogen:Synthesized peptide derived from internal of Human LILRB4.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IF; IF:1:100-1:500

Background:Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Arm J.P., J. Immunol. 159:2342-2349(1997).
Borges L., J. Immunol. 159:5192-5196(1997).
Liu W.R., Immunogenetics 51:659-669(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LILRB4

Research Areas:Epigenetics and Nuclear Signaling;Cardiovascular;Immunology