LGMN Antibody - Cat. #: CSB-PA012903LA01HU

SKU: CSB-PA012903LA01HU

Size :50ug

Clone Number:

Aliases:AEP antibody; Asparaginyl endopeptidase antibody; cysteine 1 antibody; Cysteine protease 1 antibody; EC 3.4.22.34 antibody; Legumain antibody; LGMN antibody; LGMN_HUMAN antibody; LGMN1 antibody; Protease antibody; Protease cysteine 1 (legumain) antibody; Protease cysteine 1 antibody; PRSC1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99538

Immunogen:Recombinant Human Legumain protein (199-312AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:500-1:1000

Background:Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LGMN

Research Areas:Cancer; Cell biology; Immunology; Metabolism; Signal transduction