LCAT Antibody, FITC conjugated - Cat. #: CSB-PA11369C0Rb

SKU: CSB-PA11369C0Rb

Size :50ug

Clone Number:

Aliases:LCAT antibody; LCAT_HUMAN antibody; Lecithin cholesterol acyltransferase antibody; Lecithin-cholesterol acyltransferase antibody; Phosphatidylcholine sterol acyltransferase antibody; Phosphatidylcholine-sterol acyltransferase antibody; Phospholipid cholesterol acyltransferase antibody; Phospholipid-cholesterol acyltransferase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P04180

Immunogen:Recombinant Human Phosphatidylcholine-sterol acyltransferase protein (25-433AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LCAT

Research Areas:Cancer; Cardiovascular; Metabolism; Signal transduction