LAT2 Antibody - Cat. #: CSB-PA145350

SKU: CSB-PA145350

Size :50ul

Clone Number:

Aliases:HSPC046 antibody; LAB antibody; LAT2 antibody; Linker for activation of B cells antibody; Linker for activation of B-cells antibody; Linker for activation of T cells family member 2 antibody; Linker for activation of T cells transmembrane adaptor 2 antibody; Linker for activation of T-cells family member 2 antibody; Membrane associated adapter molecule antibody; Membrane-associated adapter molecule antibody; Non T cell activation linker antibody; Non-T-cell activation linker antibody; NTAL_HUMAN antibody; WBSCR 5 antibody; Wbscr15 antibody; Williams Beuren syndrome chromosome region 15 antibody; Williams Beuren syndrome chromosome region 5 antibody; Williams-Beuren syndrome chromosomal region 15 protein antibody; Williams-Beuren syndrome chromosomal region 5 protein antibody; WSCR5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9GZY6

Immunogen:Fusion protein of Human LAT2

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:10-1:50

Background:This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LAT2

Research Areas:Immunology;Signal transduction