Lamin B1 Polyclonal Antibody

SKU: E-AB-40257

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Tags/Controls Antibodies

Abbreviation: Lamin B1

Target Synonym: ADLD;lamin B1;Lamin-B1;LMN;LMN2;LMNB;Lmnb1;LMNB1;MGC111419;OTTHUMP00000159218

Research Areas: Cancer;Cell Biology;Signal Transduction;Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P70615

Accession:

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Concentration: 1 mg/mL

Immunogen: Recombinant Rat Lamin-B1 protein expressed by E.coli

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:250-1:500;IHC 1:200-1:600

Calculated MW: 67 kDa

ObservedMW: 72 kDa