KPB2 Rabbit Polyclonal Antibody

SKU: BT-AP10877

Size:100μL

Background:Phosphorylase kinase is a polymer of 16 subunits| four each of alpha| beta| gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms| and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms| and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms| which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme| whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A| also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported| but the full-length nature of these variants has not been determined.

Research_area:Signal transduction

Target_protein:PHKA2

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:KPB2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):135850

UniProt accession:Human: P46019; Mouse: Q8BWJ3

Synonyms:KPB2

GeneID:Human: 5256; Mouse: 110094