KIF20B Antibody, Biotin conjugated - Cat. #: CSB-PA839399LD01HU

SKU: CSB-PA839399LD01HU

Size :50ug

Clone Number:

Aliases:Cancer/testis antigen 90 antibody; CT90 antibody; KI20B_HUMAN antibody; KIF20B antibody; Kinesin-like protein KIF20B antibody; Kinesin-related motor interacting with PIN1 antibody; KRMP1 antibody; M-phase phosphoprotein 1 antibody; MPHOSPH1 antibody; MPP 1 antibody; Mpp1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96Q89

Immunogen:Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KIF20B

Research Areas:Cell biology; Signal transduction