KDM2A Monoclonal Antibody

SKU: BT-MCA3798

Size:100μL

Background:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Research_area:Others

Target_protein:KDM2A

applications:

Reactivity:

Clonality:Monoclonal

Clone ID:5C11F7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:KDM2A

Immunogen:Purified recombinant fragment of human KDM2A (AA: 1-150) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):132.8kDa

UniProt accession:Q9Y2K7

Synonyms:FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA

GeneID:22992