KCNQ4 Polyclonal Antibody

SKU: E-AB-16544

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: KCNQ4

Target Synonym: DFNA 2;DFNA2;KCNQ 4;Kcnq4;KCNQ4;KQT like 4;KQT-like 4;KV7.4;Potassium channel KQT like 4;Potassium channel subunit alpha KvLQT4;Potassium voltage gated channel KQT like protein 4;Potassium voltage gated channel KQT like subfamily member 4;Potassium voltage gated channel subfamily KQT member 4;Potassium voltage-gated channel subfamily KQT member 4;Voltage gated potassium channel subunit Kv7.4;Voltage-gated potassium channel subunit Kv7.4

Research Areas: Cancer;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P56696

Accession:

Background: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human KCNQ4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:200-1:1000;IHC 1:50-1:200

Calculated MW: 77kDa

ObservedMW: