KCNA1 Polyclonal Antibody

SKU: E-AB-15740

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: KCNA1

Target Synonym: AEMK;EA1;Episodic ataxia with myokymia;HBK1;HUK1;Kca1 1;Kcna1;KCNA1;Kcpvd;KV1.1;MBK1;mceph;MGC124402;MGC126782;MGC138385;MK1;MK1;mouse;homolog of KV1.1;Potassium channel protein 1;Potassium voltage gated channel shaker related subfamily member 1;Potassium voltage gated channel subfamily A member 1;Potassium voltage gated channel;shaker related subfamily;member 1 (episodic ataxia with myokymia);Potassium voltage-gated channel subfamily A member 1;RBK1;RCK1;Shak;Shaker related subfamily member 1;Voltage gated potassium channel subunit Kv1.1;Voltage-gated K(+) channel HuKI;Voltage-gated potassium channel HBK1;Voltage-gated potassium channel subunit Kv1.1

Research Areas: Cancer;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q09470

Accession:

Background: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human KCNA1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:15-1:50

Calculated MW: 56kDa

ObservedMW: