KChIP1 rabbit pAb

SKU: ES5735

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human KCIP1. AA range:1-50

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:30820

Human_swiss_prot_no:Q9NZI2

Subcellular_location:Cell membrane ; Peripheral membrane protein . Cytoplasm . Cell projection, dendrite .

Other_name:KCNIP1; KCHIP1; VABP; Kv channel-interacting protein 1; KChIP1; A-type potassium channel modulatory protein 1; Potassium channel-interacting protein 1; Vesicle APC-binding protein

Background:This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],