JNK2 Polyclonal Antibody

SKU: D-AB-10207L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:JNK2

Target Synonym:c Jun kinase 2;C Jun N terminal kinase 2;c-Jun N-terminal kinase 2;JNK 55;JNK-55;JNK2 alpha;JNK2;JNK2 beta;JNK2A;JNK2alpha;JNK2B;JNK2BETA;Jun kinase;MAP kinase 9;MAPK 9;Mapk9;Mitogen activated protein kinase 9;Mitogen-activated protein kinase 9;MK09_HUMAN;P54a;p54aSAPK;PRKM9;Protein kinase; mitogen-activated; 9;SAPK alpha;SAPK;SAPK1a;Stress activated protein kinase 1a;Stress-activated protein kinase JNK2

Research Areas:Signal Transduction;Cell Biology;Cancer;Immunology;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P49186

Accession:

Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Concentration:1 mg/mL

Immunogen:Recombinant Human MAPK9 protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:5000-1:10000

Calculated MW:48kDa

ObservedMW:46kDa,54kDa