JAK3 Polyclonal Antibody

SKU: E-AB-31846

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: JAK3

Target Synonym: EC 2.7.10.2;JAK 3;JAK L;JAK-3;Jak3;JAK3 HUMAN;JAK3;JAKL;Janus kinase 3 (a protein tyrosine kinase;leukocyte);Janus kinase 3;Janus Kinase3;L JAK;L-JAK;Leukocyte janus kinase;LJAK;Protein tyrosine kinase leukocyte;Tyrosine protein kinase JAK3;Tyrosine-protein kinase JAK3

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P52333

Accession:

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 125kDa

ObservedMW: 125kDa