Jak3 (phospho-Tyr980/981) rabbit pAb

SKU: ES15392

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Mouse

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized phosho peptide around human Jak3 (Tyr980 and 981)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):125kD

Human_gene_id:3718

Human_swiss_prot_no:P52333

Subcellular_location:Endomembrane system ; Peripheral membrane protein . Cytoplasm .

Other_name:Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)

Background:The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],