JAK1 rabbit pAb

SKU: ES2655

Size: 100μL

Source:Rabbit

Applications:IF;WB;IP;IHC;ELISA

Reactivity:Human;Mouse;Rat

Dilution:IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human JAK1. AA range:988-1037

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):132kD

Human_gene_id:3716

Human_swiss_prot_no:P23458

Subcellular_location:Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.

Other_name:JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1

Background:This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],