ITPR2 Antibody - Cat. #: CSB-PA247118

SKU: CSB-PA247118

Size :50ul

Clone Number:

Aliases:4 antibody; 5-trisphosphate receptor antibody; Inositol 1 4 5 trisphosphate receptor type 2 antibody; Inositol 1,4,5-trisphosphate receptor type 2 antibody; Inositol 145 trisphosphate receptor type 2 antibody; InsP3 R2 antibody; InsP3R2 antibody; IP3 R2 antibody; IP3 receptor antibody; IP3 receptor isoform 2 antibody; IP3R 2 antibody; IP3R2 antibody; ITPR 2 antibody; Itpr2 antibody; ITPR2_HUMAN antibody; Type 2 inositol 1 4 5 trisphosphate receptor antibody; Type 2 inositol 1 antibody; Type 2 inositol 145 trisphosphate receptor antibody; Type 2 InsP3 receptor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14571

Immunogen:Synthetic peptide of Human ITPR2

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:50-1:200

Background:Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ITPR2

Research Areas:Cancer;Metabolism;Signal transduction