ITGA7 Antibody, FITC conjugated - Cat. #: CSB-PA618797LC01HU

SKU: CSB-PA618797LC01HU

Size :50ug

Clone Number:

Aliases:alpha 7 antibody; FLJ25220 antibody; Integrin alpha 7 antibody; Integrin alpha 7 chain antibody; Integrin alpha 7 heavy chain antibody; Integrin alpha 7 light chain antibody; Integrin alpha-7 70 kDa form antibody; ITA7_HUMAN antibody; ITGA 7 antibody; Itga7 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13683

Immunogen:Recombinant Human Integrin alpha-7 protein (175-283AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ITGA7

Research Areas:Cancer; Cardiovascular; Signal transduction