IRAK-1 (phospho Thr209) rabbit pAb

SKU: ES5914

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;IHC

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr209. AA range:175-224

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):77kD

Human_gene_id:3654

Human_swiss_prot_no:P51617

Subcellular_location:Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity). .

Other_name:IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1

Background:This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],