IQGAP3 Antibody - Cat. #: CSB-PA283992

SKU: CSB-PA283992

Size :50ul

Clone Number:

Aliases:IQ motif containing GTPase activating protein 3 antibody; IQGA3_HUMAN antibody; IQGAP 3 antibody; IQGAP3 antibody; MGC10170 antibody; MGC10831 antibody; MGC1947 antibody; OTTHUMP00000031854 antibody; OTTHUMP00000031855 antibody; Ras GTPase activating like protein IQGAP3 antibody; Ras GTPase-activating-like protein IQGAP3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86VI3

Immunogen:Fusion protein of Human IQGAP3

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IQGAP3

Research Areas:Neuroscience;Signal transduction