IQGAP1 Polyclonal Antibody

SKU: E-AB-53496

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:IQGAP1

Target Synonym:HUMORFA01;IQ motif containing GTPase activating protein 1;IQGA1;Iqgap1;KIAA0051;p195;Ras GTPase activating like protein 1;Ras GTPase-activating-like protein IQGAP1;RasGAP-like with IQ motifs;SAR1

Research Areas:Cancer;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P46940

Accession:

Background:This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Concentration:0.5 mg/mL

Immunogen:Synthetic peptide of human IQGAP1

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW:189 kDa

ObservedMW:Refer to figures