InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136)

SKU: HB782010

Size:100ug

Description:Iv0136 is a bispecific, humanized monoclonal antibody engineered for cancer immunotherapy. It simultaneously targets CD40 and 4-1BB (CD137), enabling coordinated activation of antigen-presenting cells and T cells to enhance anti-tumor immune responses. By engaging these two pathways, Iv0136 is being investigated for its potential to modulate immune activity in both oncology and autoimmune research settings. Preclinical studies indicate that dual CD40/4-1BB targeting may promote tumor control and influence immune regulation in models of diseases such as rheumatoid arthritis and multiple sclerosis.

Host species:Human

Species reactivity:Human

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG1, kappa

Applications:ELISA, Neutralization

Target:Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Accession:P25942

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID:Iv0136

Product Usage Information:

Predicted molecular weight:

Note:For research use only. Not suitable for clinical or therapeutic use.