IL11 antibody , Cat. # FNab04216

SKU: FNab04216

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production(PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation(PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

Immunogen:interleukin 11

Synonyms:Adipogenesis inhibitory factor, AGIF, IL 11, IL11, interleukin 11, Oprelvekin

Observed MW:25 kDa

Uniprot ID:P20809

Reactivity:Human, Mouse

Tested Application:ELISA, WB

Recommended dilution:WB: 1:200-1:1000

Gene ID:3589

Research Area:Immunology, Cardiovascular