IL-31 rabbit pAb

SKU: ES8589

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human IL31. AA range:21-70

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):65kD

Human_gene_id:386653

Human_swiss_prot_no:Q6EBC2

Subcellular_location:Secreted .

Other_name:Interleukin-31 (IL-31)

Background:IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008],