IL-1 beta Monoclonal Antibody

SKU: AN200016P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:IL1B

Target Synonym:IL1F;IL-1F;pro IL1F;IL-1;IL1-BETA;IL1F2;IL1 beta;IL1B;catabolin;IL-1B;pro Catabolin;pro IL1B;pro IL1F2;pro leukocytic endogenous mediator;pro leukocytic pyrogen;pro lymphocyte activating factor;pro mononuclear cell factor;IL-1F2;IL 1B;IL-1 beta

Research Areas:Immunology;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG2b

Clonality:Monoclonal

Clone NO.:7F13

UNIProt ID:P01584

Accession:

Background:Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the center region of the Human IL-1 beta

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;

Calculated MW:31 kDa

ObservedMW:18 kDa, 34 kDa, 36 kDa