IKZF3 Polyclonal Antibody

SKU: E-AB-14763

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: IKZF3

Target Synonym: AIO;Aiolos;IKAROS family zinc finger 3 (Aiolos);IKAROS family zinc finger 3;Ikaros family zinc finger protein 3;IKZF 3;IKZF3;IKZF3;zinc finger DNA binding protein Aiolos;Zinc finger protein Aiolos;Zinc finger protein subfamily 1A 3 (Aiolos);Zinc finger protein subfamily 1A 3;Zinc finger protein subfamily 1A;member 3;ZNFN1A3

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UKT9

Accession:

Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Concentration: 1.6 mg/mL

Immunogen: Recombinant protein of human IKZF3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: