IFT57 Polyclonal Antibody

SKU: E-AB-52949

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:IFT57

Target Synonym:CDNA FLJ10147 fis clone HEMBA1003369;Dermal papilla derived protein 8;Dermal papilla-derived protein 8;DERP 8;DERP8;Esrrbl 1;Esrrbl1;ESRRBL1 protein;Estrogen related receptor beta like 1;Estrogen related receptor beta like protein 1;Estrogen-related receptor beta-like protein 1;FLJ10147;Hip1 Interacting protein;HIP1 interacting protein HIPPI;Hip1 protein interactor;HIP1-interacting protein;HIPPI;Huntingtin interacting protein 1 interacting protein;Huntingtin interacting protein 1 protein interactor;IFT 57;ift57;IFT57;Intraflagellar transport 57 homolog (Chlamydomonas);Intraflagellar transport 57 homolog;Intraflagellar transport protein 57 homolog;MHS4R2;Vestrogen related receptor beta like 1

Research Areas:Cancer;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9NWB7

Accession:

Background:Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Concentration:1.5 mg/mL

Immunogen:Fusion protein of human IFT57

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:300

Calculated MW:

ObservedMW: