I-TAC Rabbit Polyclonal Antibody

SKU: BT-AP10527

Size:100μL

Background:disease:Expressed in a variety of skin disorders| including allergic contact dermatitis| lichen planus and mycosis fungoides.|Chemotactic for interleukin-activated T-cells but not unstimulated T-cells| neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.|induction:By interferon gamma and interferon beta. Induction by IFN-gamma is enhanced by TNF-alpha in monocytes| dermal fibroblasts and endothelial cells| and by IL-1 in astrocytes.|mass spectrometry: PubMed:10233762|online information:CXCL11 entry|Belongs to the intercrine alpha (chemokine CxC) family.|tissue specificity:High levels in peripheral blood leukocytes| pancreas and liver astrocytes. Moderate levels in thymus| spleen and lung. Low levels in placenta| prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.|

Research_area:Neuroscience; Immunology

Target_protein:CXCL11

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:I-TAC

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):10340

UniProt accession:Human: O14625; Mouse: Q9JHH5

Synonyms:I-TAC; C-X-C motif chemokine 11; Beta-R1; H174; Interferon gamma-inducible protein 9; IP-9; Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11

GeneID:Human: 6373; Mouse: 56066