Human Zinc Finger E-Box-binding Homeobox 1, ZEB1 ELISA Kit

SKU: E3075Hu

Size:96 Tests-1 Kit

Background:Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

Research_area:Others

Applications:ELISA

Target_protein:ZEB1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.33ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Zinc Finger E-Box-Binding Homeobox 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P37275

MASS(Da):124,074

GeneID:6935

Synonyms:Negative regulator of IL2;NIL-2-A zinc finger protein;TCF-8;Transcription factor 8;ZEB 1;ZEB1;Zinc finger E-box-binding homeobox 1

Gene names:ZEB1

Standard solution:3200ng/L