Human VAP-1/AOC3 ELISA Kit PicoKine®

SKU: EK1646

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: AOC3

Specificity: Natural and recombinant human VAP-1

Background: Amine oxidase, copper containing 3, also known as vascular adhesion protein (VAP-1) and HPAO is an enzyme that in humans is encoded by the AOC3 gene on chromosome 17. This protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family and is associated with many vascular diseases. This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.

Immunogen: Expression system for standard: NS0; Immunogen sequence: N2-N763

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Reference:

Uniprot ID: Q16853

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 8639

Protein Name: Amine oxidase [copper-containing] 3

Gene Full Name: amine oxidase copper containing 3

Synonyms: AOC3; Copper amine oxidase; HPAO; Membrane primary amine oxidase; SSAO; VAP 1; VAP1; Vascular adhesion protein 1