Human Ubiquitin-associated and Sh3 Domain-containing Protein A, UBASH3A ELISA Kit

SKU: E6375Hu

Size:96 Tests-1 Kit

Background:Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

Research_area:Others

Applications:ELISA

Target_protein:UBASH3A

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.14ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ubiquitin-associated and SH3 domain-containing protein A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P57075

MASS(Da):74,123

GeneID:53347

Synonyms:Cbl-interacting protein 4;CLIP4;STS-2;Suppressor of T-cell receptor signaling 2;T-cell ubiquitin ligand 1;TULA;TULA-1;UBASH3A;Ubiquitin-associated and SH3 domain-containing protein A;

Gene names:UBASH3A

Standard solution:2400ng/L