Human tumor necrosis factor receptor 1,TNF-R1 ELISA KIT

SKU: E4351hu

Size:96 Tests-1 Kit

Background:Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Research_area:

Applications:ELISA

Target_protein:TNFRSF1A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.28ng/ml

Detection range:0.5-150ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:tumor necrosis factor receptor 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P19438

MASS(Da):50495

GeneID:7132

Synonyms:TNFRSF1A TNFAR TNFR1

Gene names:TNFRSF1A

Standard solution:160ng/ml