Human Tryptase/TPSAB1,B2 ELISA Kit PicoKine®

SKU: EK0898

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: Tryptase/TPSAB1,B2

Specificity: Natural and recombinant human Tryptase/TPSAB1,B2

Background: Tryptases are serine proteases implicated in asthma and are highly expressed in human mast cells. They are derived from at least 4 nonallelic genes clustered on chromosome 16p13.3: TPSAB1, which represents the alpha and beta-I tryptase alleles; TPSB2, which represents the beta-II and beta-III tryptase alleles; TPSG1; and TPSD1. Elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions, but a negative test does not exclude anaphylaxis. Tryptase is less likely to be elevated in food allergy reactions as opposed to other causes of anaphylaxis.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Met1-Pro275

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Reference:

Uniprot ID: Q15661

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 7177

Protein Name: Tryptase alpha/beta-1

Gene Full Name: tryptase alpha/beta 1

Synonyms: MCP7; TPS1; TPS2; TPSAB1; TPSB1; Tryptase 1; tryptase alpha/beta 1; Tryptase beta 1; Tryptase I