Human Trichoplein Keratin Filament-binding Protein, TCHP ELISA Kit

SKU: E6318Hu

Size:96 Tests-1 Kit

Background:Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed: 15731013, PubMed: 18931701). Is a negative regulator of ciliogenesis (PubMed: 25270598).

Research_area:Others

Applications:ELISA

Target_protein:TCHP

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.45ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Trichoplein Keratin Filament-Binding Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BT92

MASS(Da):61,072

GeneID:84260

Synonyms:Mitochondrial protein with oncostatic activity;Mitostatin;Protein TCHP;TCHP;Trichoplein keratin filament-binding protein;Tumor suppressor protein

Gene names:TCHP

Standard solution:3200ng/L