Human Transmembrane prolyl 4-hydroxylase,P4HTM ELISA KIT

SKU: E7241Hu

Size:96 Tests-1 Kit

Background:Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. {ECO:0000269|PubMed:17726031}.

Research_area:

Applications:ELISA

Target_protein:P4HTM

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NXG6

MASS(Da):56661

GeneID:54681

Synonyms:P4HTM PH4

Gene names:P4HTM

Standard solution:24ng/ml