Human Transcription Factor Sox 18, SOX18 ELISA Kit

SKU: E2333Hu

Size:96 Tests-1 Kit

Background:Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers. Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17. Interaction with MEF2C enhances transcriptional activation. Besides, required for normal hair development.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:SOX18

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.25ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription Factor SOX 18

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35713

MASS(Da):40,891

GeneID:54345

Synonyms:HLTRS;HLTS;SOX18;Transcription factor SOX-18

Gene names:SOX18

Standard solution:1600ng/L