Human Transcription Factor Hes-1, HES1 ELISA Kit

SKU: E6287Hu

Size:96 Tests-1 Kit

Background:Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

Research_area:Others

Applications:ELISA

Target_protein:HES1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.54ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription Factor Hes-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14469

MASS(Da):29,541

GeneID:3280

Synonyms:bHLHb39;Class B basic helix-loop-helix protein 39;Hairy and enhancer of split 1;Hairy homolog;Hairy-like protein;HES 1;HES1;hHL;Transcription factor HES-1;

Gene names:HES1

Standard solution:3200ng/L