Human Toll-like Receptor 3, TLR3 ELISA Kit

SKU: E0365Hu

Size:96 Tests-1 Kit

Background:Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.

Research_area:Immunology; Microbiology; Signal Transduction

Applications:ELISA

Target_protein:TLR3

Reactivity:Human

Assay type:Sandwich

Sensitivity:24.94ng/L

Detection range:50-10000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Toll-Like Receptor 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O15455

MASS(Da):103,829

GeneID:7098

Synonyms:CD antigen CD283;CD283;TLR 3;TLR3;Toll-like receptor 3

Gene names:TLR3

Standard solution:12800ng/L