Human TGFB-inducible early growth response protein 1,TIEG1 ELISA KIT

SKU: E0404Hu

Size:96 Tests-1 Kit

Background:Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation. {ECO:0000250|UniProtKB:O89091, ECO:0000269|PubMed:8584037}.

Research_area:

Applications:ELISA

Target_protein:KLF10

Reactivity:Human

Assay type:Sandwich

Sensitivity:6.77ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:TGF-beta-inducible early response gene-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13118

MASS(Da):52555

GeneID:7071

Synonyms:KLF10 TIEG TIEG1

Gene names:KLF10

Standard solution:3200ng/L